If you wish to stop taking this medication, first talk to your health care provider, then taper off by slowly decreasing your daily dose. Common side effects of alprazolam include:. Clinical studies have shown that the effectiveness is limited to 4 months for anxiety disorders. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco. Do not suddenly stop taking alprazolam without talking to your doctor because you may experience harmful withdrawal symptoms. I always recommend having yearly check ups with your physician and having both kidney and liver function tests performed. Drugs Across the Spectrum.
Elderly individuals should be cautious in the use of alprazolam due to the possibility of increased susceptibility to side-effects, especially loss of coordination and drowsiness. Possible side effects include:. Although unusual, the following paradoxical reactions have been shown to occur:. Alprazolam is primarily metabolized via CYP3A4. Alcohol is one of the most common interactions; alcohol and alprazolam taken in combination have a synergistic effect on one another, which can cause severe sedation, behavioral changes, and intoxication.
The more alcohol and alprazolam taken, the worse the interaction. John's wort conversely can lower the plasma levels of alprazolam and reduce its therapeutic effect. Overdoses of alprazolam can be mild to severe depending on how much of it taken and other drugs that have been taken. Alprazolam overdoses cause excess central nervous system CNS depression and may include one or more of the following symptoms: Alprazolam, like other benzodiazepines, binds to specific sites on the GABA A gamma-amino-butyric acid receptor.
Long-term use causes adaptive changes in the benzodiazepine receptors, making them less sensitive to stimulation and thus making the drugs less potent. Withdrawal and rebound symptoms commonly occur and necessitate a gradual reduction in dosage to minimize withdrawal effects when discontinuing. Not all withdrawal effects are evidence of true dependence or withdrawal. Recurrence of symptoms such as anxiety may simply indicate that the drug was having its expected anti-anxiety effect and that, in the absence of the drug, the symptom has returned to pretreatment levels.
If the symptoms are more severe or frequent, the person may be experiencing a rebound effect due to the removal of the drug. Either of these can occur without the person actually being drug-dependent. Alprazolam and other benzodiazepines may also cause the development of physical dependence , tolerance , and benzodiazepine withdrawal symptoms during rapid dose reduction or cessation of therapy after long-term treatment.
In , Romach and colleagues reported that dose escalation is not a characteristic of long-term alprazolam users, and that the majority of long-term alprazolam users change their initial pattern of regular use to one of symptom control only when required. Some common symptoms of alprazolam discontinuation include malaise , weakness, insomnia , tachycardia , lightheadedness, and dizziness. This medication may cause withdrawal symptoms upon abrupt withdrawal or rapid tapering, which in some cases have been known to cause seizures, as well as marked delirium similar to that produced by the anticholinergic tropane alkaloids of Datura scopolamine and atropine.
To some degree, these older benzodiazepines are self-tapering. Factors that determine the risk of psychological dependence or physical dependence and the severity of the benzodiazepine withdrawal symptoms during dose reduction of alprazolam include: Alprazolam may be quantified in blood or plasma to confirm a diagnosis of poisoning in hospitalized patients, provide evidence in an impaired driving arrest, or to assist in a medicolegal death investigation. Most commercial immunoassays for the benzodiazepine class of drugs cross-react with alprazolam, but confirmation and quantitation is usually performed using chromatographic techniques.
Alprazolam is classed as a high-potency triazolobenzodiazepine: As a benzodiazepine, alprazolam produces a variety of therapeutic and adverse effects by binding to the benzodiazepine receptor site on the GABA A receptor and modulating its function; GABA receptor s are the most prolific inhibitory receptor within the brain. The GABA chemical and receptor system mediates inhibitory or calming effects of alprazolam on the nervous system.
The GABA A receptor is made up of 5 subunits out of a possible 19, and GABA A receptors made up of different combinations of subunits have different properties, different locations within the brain, and, importantly, different activities with regard to benzodiazepines. Alprazolam and other triazolobenzodiazepines like triazolam that have a triazol ring attached to their structure appear to have antidepressant properties, since the structure resembles that of tricyclic antidepressants , which also have rings.
The therapeutic properties of alprazolam are similar to other benzodiazepines and include anxiolytic , anticonvulsant , muscle relaxant , hypnotic  and amnesic ; however, it is used mainly as an anxiolytic. Administration of alprazolam, as compared to lorazepam , has been demonstrated to elicit a statistically significant increase in extracellular dopamine D1 and D2 concentrations in the striatum. The concentration of alprazolam peaks after one to two hours.
Two major metabolites are produced: The metabolites, as well as some unmetabolized alprazolam, are filtered out by the kidneys and are excreted in the urine. Alprazolam regular release and orally disintegrating tablets are available as 0. Alprazolam oral solutions are available as 0. Inactive ingredients in alprazolam tablets and solutions include microcrystalline cellulose , corn starch , docusate sodium , povidone , sodium starch glycollate, lactose monohydrate, magnesium stearate , colloidal silicon dioxide , and sodium benzoate.
In addition, the 0. Alprazolam is covered under U. Patent 3,, , which was filed on 29 October , granted on 19 October , and expired in September There is a risk of misuse and dependence in both patients and non-medical users of alprazolam; alprazolam's high affinity binding, high potency, and rapid onset increase its abuse potential. The physical dependence and withdrawal syndrome of alprazolam also add to its addictive nature. In the small subgroup of individuals who escalate their doses there is usually a history of alcohol or other substance use disorders.
Alprazolam is one of the most commonly prescribed and misused benzodiazepines in the United States. Men and women are equally likely to use benzodiazepines recreationally. The report found that alprazolam is the most common benzodiazepine for recreational use, followed by clonazepam , lorazepam , and diazepam. Regarding the significant increases detected, it is worthwhile to consider that the number of pharmaceuticals dispensed for legitimate therapeutic uses may be increasing over time, and DAWN estimates are not adjusted to take such increases into account.
Alprazolam, along with other benzodiazepines, is often used with other recreational drugs. These uses include aids to relieve the panic or distress of dysphoric " bad trip " reactions to psychedelic drugs , such as LSD , and the drug-induced agitation and insomnia in the " comedown " stages of stimulant use, such as amphetamine , cocaine , and MDMA allowing sleep. Alprazolam may also be used with other depressant drugs , such as ethanol , heroin and other opioids , in an attempt to enhance their psychological effects.
Alprazolam may be used in conjunction with cannabis , with users citing a synergistic effect achieved after consuming the combination. The poly-drug use of powerful depressant drugs poses the highest level of health concerns due to a significant increase in the likelihood of experiencing an overdose , which may cause fatal respiratory depression. A study claimed that diazepam has a higher misuse potential relative to other benzodiazepines, and that some data suggests that alprazolam and lorazepam resemble diazepam in this respect.
Anecdotally injection of alprazolam has been reported, causing dangerous damage to blood vessels, closure of blood vessels embolization and decay of muscle tissue rhabdomyolysis. Slang terms for alprazolam vary from place to place. Some of the more common terms are shortened versions of the trade name "Xanax", such as Xannies or Xanies and the phonetic equivalent of Zannies;   references to their drug classes, such as benzos or downers; or remark upon their shape or color most commonly a straight, perforated tablet or an oval-shaped pill: Alprazolam is available in English-speaking countries under the following brand names: As of December , in anticipation of the rescheduling of alprazolam to Schedule 8 in Australia—Pfizer Australia announced they would be discontinuing the Xanax brand in Australia as it is no longer commercially viable.
From Wikipedia, the free encyclopedia. For other uses, see Xanax disambiguation. D Evidence of risk. Benzodiazepine dependence and Benzodiazepine withdrawal syndrome. Drugs Across the Spectrum. Retrieved 14 September Anxiety or tension associated with the stress of everyday life usually does not require treatment with an anxiolytic Demonstrations of the effectiveness of XANAX by systematic clinical study are limited to 4 months duration for anxiety disorder and 4 to 10 weeks duration for panic disorder; however, patients with panic disorder have been treated on an open basis without any apparent loss of benefit.
The physician should periodically reassess the usefulness of the drug for the individual patient. The Most Popular Prescription Drugs". Retrieved 16 June A Review of the Literature". Comprehensive Review of Psychiatry. Principles and Practice of Psychopharmacotherapy 5th ed. Retrieved 22 January The primary care companion for CNS disorders. A Dose of Sanity: Mind, Medicine, and Misdiagnosis. Department of Health and Human Services.
Retrieved 13 February Archived from the original on 15 May Retrieved 3 April Archived from the original on 12 March Retrieved 1 October Given the millions of prescriptions written for benzodiazepines about million in , relatively few individuals increase their dose on their own initiative or engage in drug-seeking behavior. World Journal of Biological Psychiatry. Cochrane Database Syst Rev. The American Journal of Psychiatry. Archived from the original on 9 August Retrieved 2 August Archived from the original on 20 July Retrieved 3 August Archived from the original on 18 December Retrieved 7 December Archived from the original on 13 September Prediction of Alprazolam Transfer into Milk".
British Journal of Clinical Pharmacology. Fear of Teratogenic Risk and Impact of Counselling". Factors worth considering are dependency, tolerability of current medication and cost. For further information, please refer to the following links. What are the effects of taking Xanax and over-the-counter drugs, such as vitamin C, Caltrate, zinc, and Metamucil? There are no known drug interactions found between Xanax alprazolam and the following over-the-counter medications: Talk to your doctor if you have any concerns about your prescription or over-the-counter medications.
Do not start or stop any medications or treatments without first talking to your doctor. I believe you will find the following links at everydayhealth. Is long term use 20 years of Xanax harmful? I wouldn't say that it is harmful. Obviously it depends on the dose and frequency the medication is taken. In many cases, taking a Xanax alprazolam would be preferable than having alcoholic beverage for some people. I always recommend having yearly check ups with your physician and having both kidney and liver function tests performed.
However, I have yet to run into any serious consequences for people using Xanax for 20 years. Abusing the medication is a different story. Feel free to visit us here for more information: What are the possibilities of having a seizure if you take Xanax? According to Clinical Pharmacology, when taken at the recommended dose, an uncommon side effect of Xanax Alprazolam is seizures. This side effect was reported in less than 1 percent of patients taking alprazolam in clinical studies.
With short-term and long-term use of alprazolam, patients may experience withdrawal symptoms including seizures. If you experience a seizure while taking alprazolam, it is considered a serious side effect and you should contact your doctor immediately. To minimize the possibilities of this serious side effect, alprazolam should be taken only as prescribed and not with any other drugs that affect brain chemicals unless they are prescribed by a doctor who is aware of all the medications a patient is taking.
It is also important to not take the medication with alcohol. I take 6 mg of Xanax a day, along with calcium, Estroven with a multivitamin in it and flaxseed oil. Am I doing okay with what I am taking? Xanax alprazolam is a highly potent, short-acting benzodiazepine primarily used to treat moderate to severe anxiety disorders e. Generally speaking, drug interactions fall into three main categories: Drug-disease interactions may occur when an existing medical condition makes certain drugs potentially harmful.
Antacids calcium may decrease the serum concentration of benzodiazepines, however, no action is required. For more detailed information, consult with your physician or pharmacist for guidance based on your specific condition and current medications, particularly before taking any action. How long does it take to get Xanax out of your system? The average half life of Xanax alprazolam for adults is approximately The immediate release formulation has a half life range of 6.
Half life is defined as the amount of time it requires for approximately one half of the medication to be out of the system. Most sources state that it takes half lives for a medication to be completely removed from the body after stopping the medication. Therefore it would take approximately 56 hours for the medication to be out of the system. This is just an estimate as there are wide ranges in the half life values for Xanax and elimination of a medication is based on many patient specific variables.
Talk with your health care provider regarding questions and concerns you have about prescription medications. What's the difference between tramadol and Xanax? Tramadol is in a drug class called opiate agonists. Tramadol is used for the management of moderate to moderately severe pain. Tramadol works by altering pain sensation in the body. Xanax alprazolam is in a drug class called benzodiazepines. Xanax is used in the treatment of anxiety disorders and panic disorders. Xanax is thought to work by affecting brain chemicals and lessening abnormal brain excitement.
Xanax is a pregnancy category D. Xanax can cause birth defects in an unborn baby. Xanax should not be taken during pregnancy without the doctor. I have been taking Xanax for 5 years. What are the withdrawal symptoms and how long do they last? Xanax is indicated for anxiety. Common side effects of Xanax include drowsiness, dizziness, dry mouth, muscle weakness, and blurred speech. Xanax may be habit-forming and should only be taken as the doctor prescribed.
Symptoms of anxiety and restlessness may return once the Xanax is discontinued. Withdrawal symptoms may occur after using Xanax for a long period of time. Withdrawal symptoms include blurred vision, loss of appetite, diarrhea, trouble concentrating, and numbness and tingling. This is not a complete list of the side effects associated with Xanax.
For more specific information, consult with your doctor or pharmacist for guidance based on your health status and current medications, particularly before taking any action. When your doctor prescribes a new medication, be sure to discuss all your prescription and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals, and herbals, as well as the foods you eat. Always keep a current list of the drugs and supplements you take and review it with your healthcare providers and your pharmacist.
If possible, use one pharmacy for all your prescription medications and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and to advise you about drug interactions and side effects. Tell your health-care provider about any negative side effects from prescription drugs. You can also report them to the U. Food and Drug Administration by visiting www. I have been taking Xanax for several years.
I have been taking the 2 mg dose three times a day. I'm having a hard time finding a doctor and had to cut down very suddenly. I am almost out of Xanax. What can happen to me? Symptoms of anxiety or restlessness may return once Xanax is stopped. If Xanax has been taken for a long period of time, withdrawal symptoms may occur. These symptoms include blurred vision, trouble concentrating, loss of appetite, muscle twitching, diarrhea, and tingling. Is it all right to take Xanax and then take Ambien about 30 minutes later?
Will there be any interactions between the two? During use of both of these drugs, you and your doctor should watch for any excessive depression of the central nervous or respiratory symptoms. Avoid hazardous activities requiring complete mental alertness and motor coordination until you know how these two affect you. Take your medications exactly as prescribed by your doctor. According to Pfizer, the manufacturers of Xanax, there are no gluten ingredients in the brand name Xanax tablets or the generic Greenstone brand.
However, the company cannot guarantee that the ingredients they obtain from their suppliers are not tainted with gluten. How long would Xanax 2mg stay in the body if only one was taken? The elimination half-life is about Therefore in healthy adults, it would take about 56 hours to be eliminated from the body. However, the elimination of drugs depends on certain factors such as age, dosage, weight and the health of the individual. Therefore the elimination of drugs can be very patient specific.
Will my body build up a tolerance for Xanax if I need to take it daily? Benzodiazepines are classified as controlled medications. Tolerance to a medication means that a person may have to take a higher dose of the medication over time to achieve the same results or benefits as before. According to the U. Drug Enforcement Agency, repeated use of large doses, or daily use of therapeutic doses of benzodiazepines may lead to tolerance and physical dependence.
Suddenly stopping a benzodiazepine is not recommended. Withdrawal symptoms can occur if a benzodiazepine is discontinued suddenly. Withdrawal symptoms depend on the dose and length of therapy. These symptoms may include: The dose of a benzodiazepine may need to be slowly tapered if a patient needs to discontinue the medication.
What are Xanax and Valium used for? How do they work? Diazepam is used for anxiety and sometimes muscle spasms. Common side effects associated with diazepam include drowsiness, muscle weakness, and dry mouth. Other side effects may include headache, blurred vision and speech, nausea and memory problems. Typically Valium stays in the system long than Xanax. It is also important when your doctor prescribes a new medication, be sure to discuss all your medications and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals and herbals, as well as the foods you eat.
Also keep a current list of the drugs and supplements you take and review it with your healthcare provider and your pharmacist. I have been taking Xanax for 3 to 4 years. Do I need to be weaned off and how? Is it wise to stop cold-turkey? Xanax alprazolam is a benzodiazepine used for the treatment of anxiety disorders. Withdrawal symptoms can occur with abrupt discontinuation of Xanax especially in patients on high doses or those who have been on the medication long term.
Withdrawal symptoms from stopping Xanax too quickly may include; tremor, sweating, trouble sleeping, muscle cramps, stomach pain, vomiting, or unusual behavior. According to the packaging information, abrupt discontinuation of Xanax should be avoided. It is recommended to decrease the dose by 0. Your doctor will be able to recommend a dosage taper for you. It is important to learn how to cope with everyday stress. Some alternative ways to help deal with stress include exercise taking a walk, yoga , enjoying some fresh air, spending time with friends or family that you enjoy, and focusing on the positive things in life.
Your healthcare provider may be able to provide you with other suggestions. If you need to use Xanax, but don't feel you need it every day, is that acceptable? Xanax alprazolam is a sedative that belongs to the class of drugs known as benzodiazepines. It is a short-acting medicine for anxiety disorders. The use of Xanax on an as-needed basis is common practice as it allows for more patient control over symptoms, may be helpful for short-term situations that cause fear or anxiety, and may decrease the overall use of the medication.
However, it is important that you follow the directions provided by your doctor and use Xanax as labeled. Xanax can be habit forming. Do not change your dosage without speaking to your doctor first. Always keep a current list of the drugs and supplements you take and review it with your health care providers and your pharmacist. My mom's friend just had a very bad stroke and she has lupus so she is on prescription medication such as Valium, Percocet, methadone, and a few more.
Can an overdose of Xanax be the reason she had this stroke? There's also a possibility that she could has had an alcoholic beverage. There is no mention of stroke due to overdose in the prescribing information for Xanax. Some of the problems that can occur when there is an overdose of Xanax include: Death from overdose of Xanax has also occurred in combination with alcohol use.
For more specific information, consult with a doctor for guidance based on her health status and current medications, particularly before taking any action. I picked up my Xanax 1 mg. They gave me the oval blue pill form with "" and "V" on the bottom. It's the same size as Xanax 1 mg, but I've never seen one like it. Is it the same? The pill you described as blue, oval-shaped and marked " V" is identified to be alprazolam 1 mg Xanax manufactured by Qualitest Pharmaceuticals Inc. There are numerous manufacturers of generic medications on the market, and sometimes the manufacturers supplying the generics to your local pharmacy change.
The active ingredient in this medication is still alprazolam, which means it should work the same. However, the inactive ingredients may be different from other generics you have been getting. Some patients react differently and negatively to a different generic medication than the one they have been taking. If that is the case with you, consult with your pharmacist for guidance, particularly before taking any action. I take Xanax and have been diagnosed with glaucoma. What other medications are safe with this condition?
When anxiety cannot be treated with benzodiazepines, such as Xanax alprazolam , other medications, such as Buspar buspirone or antidepressants, such as the SSRIs selective serotonin reuptake inhibitors , Prozac fluoxetine , Zoloft sertraline , Paxil paroxetine , or Celexa citalopram , or the SNRIs serotonin-norepinephrine reuptake inhibitors Cymbalta duloxetine or Effexor venlafaxine can be used. Antidepressants work because they act on neurotransmitters that are involved in depression and in anxiety.
Side effects from these groups may include nausea, dizziness, insomnia, gas, and impotence. Earlier generation antidepressants, such as MAO monoamine oxidase inhibitors and TCA tricyclic antidepressants can also be used for anxiety, but they have more side effects, include cardiovascular, so they are not used as much. In addition to medications, anxiety can often be successfully treated with psychotherapy alone, or along with medication. Psychotherapy can help a person find the triggers to their anxiety and help them find ways to cope with the issues.
There are two types of therapy. One focuses on behavior and how to change behavior to cope. The other is cognitive therapy, which helps a person alter their thoughts to minimize the symptoms of anxiety. A general practitioner can recommend a psychologist who can help manage anxiety with the best treatment option for that person. What are the long-term effects of Xanax? Long term use of Xanax can lead to physical or psychological dependence on the medication. Patients who have been on Xanax long term that plan to stop the medication need to taper the dose down slowly to avoid or lessen the amount of withdrawal symptoms experienced.
Possible withdrawal symptoms with Xanax include tremor, sweating, trouble sleeping, muscle cramps, stomach pain, vomiting, or unusual behavior. One of the main side effects of Xanax is central nervous system depression which can impair mental and physical abilities, this can occur even with short term use. It is important to avoid alcohol use while on Xanax. What would a round white pill marked R be? The pill with the imprint R is alprazolam 0.
Xanax alprazolam is a benzodiazepine that works on chemicals in the brain that become unbalanced. It's used to treat anxiety. Will long-term use of Xanax. Xanax alprazolam is in a group of drugs called benzodiazepines which affect chemicals in the brain that may become unbalanced and cause anxiety. The drug is designed to correct a chemical imbalance in the brain which is causing anxiety.
There are long-term side effects of using Xanax such as drowsiness, dizziness, feeling irritable, amnesia or forgetfulness, trouble concentrating, sleep problems insomnia , muscle weakness, lack of balance or coordination, slurred speech, blurred vision, and loss of interest in sex to name a few. If you are experiencing specific side effects you are concerned about, consult your doctor. You can also find helpful information on Xanax at http: I am taking generic Xanax.
Consult with your health care provider about changing your dose or sleep concerns. It is important when your doctor prescribes a new medication, be sure to discuss all your prescription medications and over-the-counter drugs, including dietary supplements, vitamins, botanicals, minerals and herbals, as well as foods you eat.
If possible, use one pharmacy for all your prescriptions and over-the-counter products. This allows your pharmacist to keep a complete record of all your prescription drugs and advise you about drug interactions and side effects. My year-old mother's doctor prescribed Xanax to help her sleep at night. What is it usually prescribed for? Xanax is used in the treatment of anxiety disorders, such as generalized anxiety disorder. Xanax is also used for the short-term relief of anxiety symptoms.
Xanax is also used to treat panic disorders. According to Xanax's prescribing information, generalized anxiety disorder is defined as a anxiety that is not realistic or excessive, and b worry about two or more life circumstances, which lasts for 6 months or more and is present on more days than it is absent. At least 6 of the following symptoms are usually present in people with generalized anxiety disorder: According to Xanax's prescribing information, anxiety associated with depression is responsive to Xanax.
Panic disorder is defined as unexpected panic attacks that keep happening. Specifically, a panic attack is a period of intense fear or discomfort that develops all of a sudden and reaches a peak with 10 minutes. Four of the following symptoms develop: For more specific information, consult with your mother's doctor for guidance based on her health status and current medications, particularly before taking any action.
How safe is Xanax during pregnancy if only needed occasionally? Xanax alprazolam is classified as pregnancy Category D, which means it is not recommended for use during pregnancy because it can cause birth defects in an unborn baby. Xanax belongs to a class of drugs called benzodiazepines, which if taken by a pregnant woman, can enter the fetus through the placenta. Withdrawal symptoms have been described in newborns whose mothers took Xanax during pregnancy. Before taking Xanax during pregnancy, you should discuss the risks and benefits of using it with your doctor.
What are the effects of Xanax on the memory? Xanax alprazolam is an anxiolytic medication classified as a benzodiazepine. The exact mechanism of action of the benzodiazepines is not clearly defined. However, it is known that the benzodiazepines demonstrate depressant activity in the central nervous system. Xanax is indicated for the treatment of panic disorder and the management of anxiety disorders and anxiety associated with depression.
According to the prescribing information, the reported adverse effects of benzodiazepines on the memory include concentration difficulties, transient amnesia or memory impairment.