Unfortunately, whilst you are gone a thunderstorm breaks overhead. He prefers it to alprazolam Xanax as it won't cause paradoxical excitement, increased aggression, or addiction. When used continuously, they create a physical dependence. Other combinations that may be effective include combining Prozac with buspirone or Elavil, or combining Elavil with beta plockers, such as propranolol. TCAs can cause bone marrow suppression. Can I give her more? Last, but not least, is Thundershirt.
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|Alprazolam for dogs 1mg||Enter your e-mail address to get a secret discount code for your dogs purchase: Consequently, since one cannot accurately alprazolam the exact onset or duration for a thunderstorm while away from home for long periods of time, Xanax provides superior results. 1mg a medium-sized dog, starting with an initial 0. If your super-stressed noise phobic dog would sleep through the next July 4 celebrations then everyone is happy. Select Your Medicare Alprazolam. When used in pets, Xanax may 1mg excessive lethargy or sedation. Ffor dogs of appetite is for common, but usually goes away after a few days.|
|Alprazolam for dogs 1mg||The dogs common side effect alprazolam TCAs is sedation. Covered medications include Amitriptyline, Fluoxetine and Buspirone. Veterinarians commonly prescribe fluoxetine when treating alprazolam anxiety, various dogs of state anxiety, and obsessive-compulsive disorders. Xanax may also be useful in the treatment of irritable 1mg syndrome. But if used rationally in for dog that has had a complete physiologic and laboratory evaluation that showed no abnormalities, the benefits of this drug class can be great and the risks few. Lately, veterinarians have placed greater emphasis for training and behavior, and specialists working in the field of animal behavior have increasingly adopted drugs employed in human behavior modification for use in 1mg animals.|
Alprazolam is useful in cases where your pet is otherwise unable to control their anxiety, helping them reclaim their life. Due to the effects this drug has on the brain, along with our limitations in understanding how the brain actually works, certain vets advise against giving this drug to pets exhibiting signs of aggression , warning that the effect of alprazolam is just strong enough to rid these pets of the very anxiety that is holding back their aggressive outbursts.
Alprazolam should be given cautiously to pets with liver or kidney disease , glaucoma , pregnant , are elderly , or in a debilitated condition. Taking alprazolam with antacids might slow the rate of absorption, and the two medications should be separated by at least two hours if being taken concurrently. Drugs like cimetidine , erythromycin, itraconazole, ketoconazole , propranolol, or valproic acid might decrease the metabolism of alprazolam, and cause an increase in sedition.
Flumazenil might reverse the effects of alprazolam, making it useful in the event of an overdose. The effects of digoxin might be increased if taking with alprazolam, and should be monitored. In general, taking alprazolam with barbiturates or other CNS depressants might increase the sedative effects. Hepatic enzyme inhibitors might alter the metabolism of other cytochrome P metabolized drugs. However it can be prescribed legally by a vet as there is no veterinary alternative to this medication.
For the best effects, behavior modification therapy should be done in conjunction with the treatment. The most common side effect of alprazolam is sedation, along with the inability of your pet to benefit from the behavior modification. In some rare cases, and mostly in dogs, the sedative effects of the drug may actually become reversed, having an energizing effect of the dog.
In cats, however, the side effects tend to be an increase in affection, strange behavior, irritability, and possibly even an increase in depression. Sounds that had never before bothered her, such as lawnmowers, leaf blowers, loud trucks, and even the sound of other dogs barking, now frightened her. Most of our walks were spent trying to avoid these noises, and when she did hear them, she wanted to turn around and go home.
Eventually, Piglet was startled on a walk by a loud chirping noise from a ground squirrel. After that, she began waking at dawn, reacting to the sound of birds in my yard. Soon she was spending most of the night awake, pacing, panting, unable to rest and pawing at me to get up as well. Her noise phobias had escalated to generalized anxiety disorder GAD. Neither of us could live like this. We had to find something to help.
All of these are prescription medications. It is important that you work closely with your veterinarian, or with a veterinary behaviorist, when using anxiolytic drugs. It is also important to do behavior modification as well, as drugs alone will rarely resolve a severe anxiety problem by themselves, just as behavior modification alone often will not work without drugs. A dog behaviorist veterinary or otherwise can help you with this. Following is a summary of the different types of anti-anxiety drugs, what they are commonly used for, and what you need to know before using them.
With the exception of clomipramine, the FDA has not approved the use of these drugs in dogs, as the drug companies have not submitted the necessary research. However, many of these drugs were tested on animals before use in humans, and they have been used off-label by many vets. Some of the following is taken from that source, and some from various papers written by noted veterinary behaviorist Dr.
Karen Overall and other veterinarians. See below for more information on dosages, interactions, side effects and contraindications. Sileo dexmedetomidine oromucosal gel , designed for pet owners to administer before or at the time of a fear or anxiety-eliciting noise stimulus, is the first FDA-approved treatment specifically for noise aversion. Introduced in by Zoetis, Sileo has a rapid speed of onset, typically taking effect within 30 to 60 minutes after application. It is squirted into the cheek pouch, and each dose lasts two to three hours.
Sileo can be redosed as needed every two hours, up to a total of five doses per event. The company says that the tube is only good for 48 hours after opening, though at least one person reported it lasting longer. If anyone tries this product, I'd be interested in hearing your feedback. The effects of BZs do not last very long, usually only a few hours. When used continuously, they create a physical dependence. Benzodiazepines commonly used with dogs include alprazolam Xanax , clonazepam Klonopin , and diazepam Valium.
These drugs are used to treat anxiety, noise phobias including thunder phobia , panic attacks, and separation anxiety. They should be used with caution in fear-aggressive dogs, as they may lower fear-based inhibition and increase the likelihood of the dog biting. Their safety range is very wide, and they can be combined with most other medications, including TCAs and SSRIs, as well as with pain medications such as tramadol. They can also be used together with dosage of each reduced proportionately.
As with all anti-anxiety medications, you should start with a low dose and increase only as needed. Dodman has had a lot of problems with Xanax alprazolam causing paradoxical excitement in dogs. He now prefers using Clonidine instead when quick action is needed. Clonidine helps with storm phobias, noise phobias, separation anxiety, and other types of fear-based behavior problems. See Other Drugs below for more information. A combination of Prozac fluoxetine and Clonidine would be his first choice now for dogs with storm phobias, while in the past he has used clomipramine and alprazolam Clomicalm and Xanax.
Because of their addictiveness, Dr. Dodman feels benzodiazepines should be used only as needed, not on a regular basis. It takes effect very quickly, within 20 minutes of being given, and does not tend to cause sedation. Alprazolam has some effect if given after the dog becomes anxious, but it works far better if given ahead of time.
For dogs with thunder phobia, it should be given whenever a storm is expected, rather than waiting until it arrives, though more can be given at that time, if needed. The recommended dosage range is quite wide, with the highest dose being 10 times the lowest dose. Clonazepam is used less frequently than alprazolam, as it takes a little longer to be effective, but it is also longer lasting.
There are two recommended dosage levels for clonazepam: It is important to be aware of this, as the dosage for seizure control is much higher than that used for anxiety. I was reassured to me to realize how high a dose could be given without being dangerous. Diazepam is more sedating than the other drugs in this class, and may have less anxiolytic effect, so it is generally not recommended for anxiety.
It is the shortest-acting of this drug class in dogs, and does not take effect as quickly as the others. I found an article by Dr. I started Piglet at 0. I started by giving Piglet this dosage of alprazolam whenever she would wake me up, which was generally a couple of hours after we went to sleep. She would usually settle down within an hour after getting the medication.
My vet then suggested that I give an increased dosage of alprazolam at bedtime, before Piglet became anxious. Rather than giving her 0. This made a huge difference. The alprazolam did not sedate Piglet; it just relaxed her enough to be able to sleep, without anxiety waking her up during the night. By giving it to her before she became anxious, she was able to sleep through most of the night.
After consulting with a veterinary behaviorist, I started giving Piglet 1 mg alprazolam every eight hours, to try to prevent her from becoming anxious. Her anxiety was under control, but she seemed to be on something of a roller coaster, becoming more reactive each hour after the alprazolam was given. I generally had to get up once during the night to give her a dose, as it was too short-acting for her to be able to make it all the way thru the night without waking and becoming anxious.
I decided to switch to clonazepam, as its effects last longer. Because the recommended dosage range of clonazepam for anxiety in dogs is similar to that for alprazolam, I tried giving Piglet the same dosage 1 mg , but quickly found out that was not enough. I increased the dosage to 2 mg 0. I gave this amount twice a day, at bedtime and after breakfast. With clonazepam, Piglet was able to sleep through the whole night. Because buspirone has few side effects and does not cause sedation, it is an excellent first choice for treating dogs with aggression or anxiety that is not too severe.
It must be given continuously for at least four to six weeks in order to determine whether or not it will help. I learned about buspirone from Amy Cook , a dog trainer in Oakland, California, who has a special interest in fearful dogs. Amy has dealt with fear and anxiety in many dogs, including two of her own, and has learned a lot about the medications used for treatment. Dodman's first choice for treating generalized anxiety and noise phobias, but he says it's important to give a high enough dosage.
Buspirone also helped a client's dog that was growling and urine-marking after the arrival of a new baby. That dog responded wonderfully to Buspirone and was able to return to her flyball team with the help of this medication. We started Piglet on a low dose 10 mg, or 0. Unfortunately, it did not help, and I weaned her off it. Combining Clomicalm with behavior modification therapy BMT for separation anxiety achieves a faster response than using BMT alone, but after three months, the results are similar.
The tricyclic antidepressants most commonly used with dogs are amitriptyline Elavil and clomipramine Clomicalm. The general recommendation is to start with a low dose, then increase every two weeks as needed. The most common side effect of TCAs is sedation. Anorexia loss of appetite is also common, but usually goes away after a few days. Giving with food and dividing the dosage between meals may decrease gastric side effects.
Dodman feels amitriptyline is not as effective as clomipramine. Prozac is equally or more effective than clomipramine, and is safe and inexpensive, so it would be a better choice than amitriptyline, but his preferred medication for anxiety is Buspirone see above. My own vet prefers to use amitriptyline as the first choice when treating anxiety, not because it is the most effective drug, but because he feels it is safer than clomipramine.
It is also inexpensive. It is well suited to dogs with relatively mild anxiety disorders, including anxiety-related aggression and submissive urination. It is not useful for compulsive disorders. Amitriptyline can relieve chronic pain, and has some action as an antihistamine. Clomipramine is best suited for situations involving anxiety, including separation anxiety, as opposed to reactivity.
Clomipramine is also very effective at treating compulsive disorders. TCAs can cause bone marrow suppression. With my veterinarian's guidance, I started Piglet on 25 mg 1. Piglet tolerated the drug very well, and she did not have problems with sedation or other side effects. However, as time went on, I noticed no improvement in her behavior, even after we increased the dose, so I weaned her off it.
We started at 20 mg 1. After two weeks, I increased to 25 mg 1. Again, Piglet tolerated it well; she had no stomach upset, and blood work was normal after two weeks. She was on clomipramine for a total of only three weeks before I began weaning her off, as I did not feel it was helping, but in retrospect, I realize that she got much worse when I weaned her off the drug.
Because of their safety margin, Dr. Dodman does not feel it is necessary to do blood work or other tests prior to starting healthy dogs on SSRIs. All of the follow-up blood work he has done over twenty years has been normal. Aggression and separation anxiety generally respond very quickly within a week to the use of medications, while depression and compulsive behavior may take up to several months. Tryptophan, an amino acid supplement, can be combined with Prozac for dogs with low serotonin levels.
Buspirone can also be combined with Prozac to increase the release of serotonin. Serotonin-enhancing drugs help in fearful conditions by stabilizing mood. These include "social anxiety," storm phobia, noise phobia, and separation anxiety. It is important to do blood work before starting, especially for older dogs, and monitor periodically after that. SSRIs can be combined with TCAs using low-end doses of each, which may help them take effect faster and lessen the chances of side effects.
Others include sertraline Zoloft and paroxetine Paxil , all with similar potential side effects, though paroxetine is more difficult to wean off and may have a shorter half-life, leading to more variation in its effects. The usual methodology is to start with a low dosage, and then increase if no improvement is seen after weeks. Treatment must continue for at least weeks before you can know for sure whether it helps. Fluoxetine is used to treat aggression, obsessive-compulsive disorders, separation anxiety, panic and avoidance disorders, including post-traumatic stress disorder.
Fluoxetine works well for conditions involving reactivity, including some forms of aggression. Paroxetine is used to treat depression, social anxiety, and agitation associated with depression. Sertraline is useful particularly for generalized anxiety and panic disorder. After consulting with the veterinary behaviorist, we started Piglet on fluoxetine, at a low dose of 10 mg 0.
Piglet did have some loss of appetite with this medication. Fortunately, after about a week, this problem went away. It also seemed to sedate her for the first couple of days, but she was normal after that. Her blood work was fine when we rechecked it a couple of weeks after starting the drug. The fluoxetine was helping, but I still felt that she was on edge and overly reactive.
I decided to make one further change and switch her to sertraline instead of fluoxetine. Sertraline is long-acting, similar to fluoxetine, which is desirable. I did discover that it was much more expensive, as there was no generic available at the time a generic version has since been released and is quite inexpensive, see Cost Comparison below. We started Piglet on a once-a-day dose of 25 mg 1.
I wanted to use tramadol , an effective prescription pain reliever, but had seen warnings about combining it with SSRIs, due to the risk of serotonin syndrome, though I later learned that this could be done with caution. In fact, she became almost normal again. I believe that she must have been experiencing some chronic pain that lowered her anxiety threshold. I also think that the small tumor in her foot may have been bothering her for a long time, though I was unaware of it.
For the next few months after the surgery, Piglet did not have a single anxiety attack. She had a few minor episodes, where she became restless, with some pacing and attention-seeking behaviors, but no panting, trying to hide, waking me up at night, etc. These episodes did not last very long, usually only about minutes, before she was able to settle down again. At this time, I was giving her sertraline 25 mg once a day and clonazepam 2 mg, twice a day.
I spent another couple of months trying different things. I put her back on Metacam and added tramadol, in case pain was still contributing to her anxiety, but that also did not help. She was not as bad as she had been originally, but she was still having full-blown anxiety attacks periodically, and was on edge most of the time.
After discussion with my veterinarian and the veterinary behaviorist, we increased Piglet's clonazepam to 3 mg 0. This helped some, but not enough. I finally decided to increase her SSRIs, though both my vet and the veterinary behaviorist were concerned with doing this. Because fluoxetine Prozac is considered to be two-and-a-half times as effective as sertraline Zoloft at the same dosage level in humans, but the dosage ranges given for dogs are similar, I twice tried to switch Piglet from sertraline to fluoxetine, but both times she got much worse and I switched her back.
I then increased her sertraline dosage from 25 mg to Within a few days, she was back to normal. That was over three months ago, and she has continued to do great since. On the rare occasion that she starts showing signs of anxiety, or if I have to leave her alone for too long, I give her melatonin 3 mg plus a very small dose of alprazolam 0. I am in the process of very slowly reducing her clonazepam dosage it is addictive, so I am making only small changes every two weeks , and she is continuing to do well with the reduced dosage.
I no longer question the impact of these slower-acting drugs. If needed, you can combine them with the quicker-acting benzodiazepines to get some relief while waiting for the other drugs to take effect. Piglet enjoys her walks and explores new places again, and no longer avoids the areas where she might hear loud noises. She sleeps thru the night peacefully and is relaxed during the day, even playful again.
She is more interested in everything. Although only the benzodiazepines are physically addictive, it is important to wean off all anti-anxiety medications slowly, reducing dosage gradually every one to two weeks, rather than stopping abruptly. Stopping benzodiazepines too quickly can lead to seizures; they must be weaned slowly as they create physical dependence. I have learned that when you find medications that work, you need to continue to give them for some time. A dog must be treated with SSRIs or TCAs for a minimum of three to five weeks before you are able to assess the effects; then, you must maintain treatment until all the dog's symptoms are gone or are at the same low, consistent level, for at least another one to two months.
Treatment should be continued after that for at least as long as it took to achieve that level, before even beginning to think about weaning them off. Total length of treatment should be a minimum of four to six months. One of the mistakes I made was always trying to give the minimal drugs possible; every time I would see improvement, I would try to reduce the amount of drugs she was getting, and then she would get worse again.
I have learned that it takes time to overcome anxiety disorders; they do not go away overnight. If needed, I am prepared to keep Piglet on these drugs for the rest of her life. She is tolerating them well, with no side effects and continued normal blood work, and the improvement in her quality of life is so dramatic that I no longer fear having her on them. I have come to realize that there is no harm in relying on drugs when they are needed.
In hindsight, I wish I had tried using alprazolam for our walks when Piglet's reaction to outside noises first escalated; I think she would not have gotten so bad if I had treated the problem early. I would never recommend anxiety drugs as a first choice, before trying to address anxiety with natural methods, but when a dog's quality of life is at stake, the drugs can perform miracles.
They have given Piglet back her life, and for that I am grateful. Piglet is now 15, and still doing great. She continues to take the same dosage of sertraline It appears she will need to stay at that level, as she has developed problems when I tried to reduce it further. I continue to give melatonin 1. On the rare occasion that her anxiety escalates usually, I believe, due to vomiting medication , I give more alprazolam every half hour to an hour until she settles down.
She is doing great overall, still enjoying her walks and no longer letting anxiety ruin her life. She had some problems with "breakthrough" anxiety last fall, and I ended up increasing her dosage of sertraline to 50 mg daily. Clonazepam remains at 1 mg in the morning and 2 mg at night. She has not needed any extra medications in seven months, other than the small amount of alprazolam plus melatonin that I give prophylactically when I have to leave her for long periods at night.
Piglet just turned Because she has been doing so well since increasing her sertraline to 50 mg once a day, I have gradually reduced her dosage of clonazepam from 3 mg daily 1 mg AM and 2 mg PM to 1 mg in the AM only. Interestingly, although she had no problems with the reduction, she did react when I tried to eliminate that last 1 mg, so I'm leaving her on that. I have not needed to give her any extra medication, even when I have to be gone for long periods.
Piglet was euthanized on March 5, , at the age of She had lost most of her vision due to a combination of factors, and had developed canine cognitive dysfunction. As a result, she was getting stuck in corners and could no longer enjoy her walks, or her life. I made the difficult decision to let her go. Looking back on her life after she was gone, I became more aware of how different Piglet was after developing generalized anxiety disorder, even when the medications were able to keep her symptoms under control well enough for her to function.
My takeaway message is to take early signs of anxiety seriously, and to start medication sooner rather than later, particularly if signs are getting worse. Do whatever is necessary to shield your dog from whatever is causing anxiety, and use medications along with behavior modification to prevent anxiety and phobias from taking over your dog's life. Dosages below are given in mg milligrams per kg kilogram of body weight of the dog. Note that some of these drugs are available in liquid form if smaller doses are needed, or you could use a compounding pharmacy.
When using benzodiazepines for noise phobias or separation anxiety, it is best to give them one to two hours before the anticipated noise or stimulus, and then repeat as needed. Benzodiazepines should not be given with the antifungal medications ketoconazole or itraconazole. Cimetidine Tagamet , erythromycin, propranolol and valproic acid will slow the metabolism of these drugs and can create excessive sedation. Antacids decrease absorption and should be given separately, at least two hours apart.
Benzodiazepines should be used with caution in the case of liver or kidney disease, or narrow angle glaucoma. Side effects such as sedation or increased appetite usually go away with continued usage. Dodman says that when buspirone doesn't work for anxiety issues, it is usually due to the dosage being too low.