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While the margin of safety is very high in our pets, accidental overdose can occur. However it can be prescribed legally by a vet as there is no veterinary alternative to this medication. Home Wellness Medication Guides. Taking alprazolam with antacids might slow the rate of absorption, and the two medications should be separated by at least two hours if being taken concurrently. Dog unable to move. She created Ask A Vet Question as a resource for good, accurate veterinary advice online.
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Information for Medical Professionals. A study of the elderly who were benzodiazepine dependent found withdrawal could be carried out with few complications and could lead to improvements in sleep and cognitive abilities. British Journal of Clinical Pharmacology. There is no evidence that "drug holidays" or periods of abstinence reduced the risk of dependence; there is evidence from animal studies that such an approach does not prevent dependence from happening. Withdrawal symptoms include anxiety, perceptual disturbances, distortion of all the senses, dysphoria, and, in rare cases, psychosis and epileptic seizures. The differing speed at which tolerance occurs to the therapeutic effects of benzodiazepines can be explained by the speed of changes in the range of neurotransmitter systems and subsystems that are altered by chronic benzodiazepine use. Many patients know that the benzodiazepines no longer work for them but are unable to discontinue benzodiazepines because of withdrawal symptoms.
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